cellcyclecheckpointreview

由 RT Abraham 著作 · 2001 · 被引用 2729 次 — The overall function of these checkpoints is to detect damaged or abnormally structured DNA, and to coordinate cell-cycle progression with DNA repair. Typically ...

由 R Visconti 著作 · 2016 · 被引用 329 次 — In this review we summarize developing concepts on how targeting cell cycle checkpoints may provide substantial improvement to cancer therapy.

由 A Panagopoulos 著作 · 2021 · 被引用 52 次 — Cell cycle checkpoints secure ordered progression from one cell cycle phase to the next. They are important to signal cell stress and DNA ...

由 SK Panda 著作 · 2019 · 被引用 10 次 — 1–5 This review intends to introduce the basics of the cell cycle and its regulation at different checkpoints in relation to cancer. Cancer is broadly a result ...

How cells use checkpoints at the end of G1 phase, end of G2 phase, and partway through M phase (the spindle checkpoint) to regulate the cell cycle. Introduction.

由 MB Kastan 著作 · 2004 · 被引用 3628 次 — Highly conserved DNA-repair and cell-cycle checkpoint pathways allow cells to deal with both endogenous and exogenous sources of DNA damage. How ...

由 M Molinari 著作 · 2000 · 被引用 458 次 — Checkpoints are mechanisms that regulate progression through the cell cycle insuring that each step takes place only once and in the right sequence.

由 KJ Barnum 著作 · 2014 · 被引用 695 次 — Cell cycle checkpoints are surveillance mechanisms that monitor the order, integrity, and fidelity of the major events of the cell cycle.

由 A Murray 著作 · 1994 · 被引用 304 次 — Checkpoints help ensure that cell cycle events occur in the correct order. Studies on mammalian cells identified inhibitors of complexes of cyclins and ...

由 EM Gordon 著作 · 2018 · 被引用 93 次 — The purpose of the present study is to provide a focused review of cycle checkpoint control as a practicum for clinical oncologists with an ...